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Dr. Peter R. Bernstein

PhaRmaB LLC

 

Member profile details

Photo
First name
Dr. Peter R.
Last name
Bernstein
Organization
PhaRmaB LLC
 

Contact information

City
Philadelphia
State or Province
Pennsylvania
Zip Code
19102
Country
United States
Phone
(610) 233-6523
Fax
(610) 891-9508
 

Specialties and Services

Fields of Expertise
  • Expert Witness
  • Medicinal Chemistry
  • Organic Chemistry
  • Pharmaceutical
  • Synthesis
Other Fields of Expertise
Medicinal Chemistry and problem solving in small-molecule drug discovery projects
Due Diligence
Portfolio Review
Summary
Dr. Bernstein has an exceptional track record with over 30 years of success in industrial research [ICI Pharmaceuticals, Zeneca Pharmaceuticals and AstraZeneca Pharmaceuticals]. He provided scientific and project leadership to groups that advanced >10 candidates into preclinical development and 5 into clinical studies. One of the programs/compounds he worked on led to Accolate™ [a first-in-class CysLT1R antagonist for asthma], other compounds from his teams [such as AZD5213] remain under clinical development. He has made broad contributions to medicinal chemistry and to the scientific community that have been recognized by awards and honors. He is the co-inventor of ~90 issued patents and co-author of ~ 130 publications and presentations. Due to his love of medicinal chemistry and of helping other scientists to develop Dr. Bernstein has remained engaged in a broad array of professional activities since his retirement from AstraZeneca. In addition to consulting he is active as: editor, writer, and scientific conference organizer/participant.
Services
PhaRmaB was established in October 2010 to provide a platform from which Dr. Bernstein could respond to requests for his services.

Medicinal Chemistry:
PhaRmaB provides world-class expertise in all phases of small molecule drug discovery including: Target Identification, Lead Identification [Hit-to-Lead], Lead Optimization, Candidate nomination, Clinical Candidate support and post launch product support. The company president’s experience includes: structure-based design, screening libraries design, privileged structures, optimization of DMPK parameters with reduction of off-target activities and as drug target areas: G-protein coupled receptors, enzyme inhibitors, ion-channel ligands, transporter inhibitors and nuclear hormone modulators.

Due diligence:
PharmaB LLC has experience in drug licensing, including due diligence activities. Services include third-party evaluation of lead and/or candidate structure and data.

Portfolio Review:
Dr. Bernstein has extensive experience in senior level project and portfolio reviews in many functions including: neuroscience, psychiatry, pain, respiratory, inflammation, oncology, safety assessment, and core chemical sciences.

Expert Witness:
PharmaB LLC provides expert witness support for patent litigation.
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