Chemical Consultants Network ZOOM MEETING

BEHIND THE “VIEW”- PET TRACER SYNTHESIS AND FORMULATION

Youwen Xu – Independent Consultant & Contractor

DATE & TIME:  Wednesday, February 10, 2021 at 6:30 pm

Location:  Online via Zoom! (registration required, see below)

Abstract: Positron emission tomography (PET) is a unique non-invasive imaging tool for studying the in vivo biological process. It utilizes short-lived positron emitter labeled organic molecules to study the biological events in real time. The common positron emitters are F-18 (t 1/2 = 109.8 min), C-11 (t 1/2 = 20.4 min), N-13 (t 1/2 = 9.96 min), O-15 (t 1/2 = 2.05 min) and various of radio metals. To incorporate the positron emitters into a molecule of biological interests rapidly and preferably with mild reaction condition, radioactive synthons are often developed to facilitate the facile labeling radiochemistry. This presentation will briefly discuss the rich chemistry that enables the imaging for disease diagnostic and therapeutic application.

Biography: Youwen Xu currently works as an independent consultant/contractor in radiopharmaceutical development and validation in drug development. Youwen was a scientist in the Radiochemistry, Instrumentation and Biological Imaging (RCIBI) program of Brookhaven National Laboratory (2001 – 2015, Upton, NY) with expertise in radiopharmaceutical development and validation and in vivo PET imaging study in animal and human subjects. Youwen joined Eli Lilly (2016-2018, Philadelphia, PA) as a senior radiochemist and served as the radiochemistry support team lead for the Discovery Research in new Alzheimer’s disease imaging agent discovery program. She has authored and co-authored about 50 peer reviewed publications. She started to participate in and became associated with CCN activities since 2018.

Reservation: Use the register button to register for this meeting. The Zoom link will arrive via email