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Princeton ACS Dinner Meeting - “Practical Considerations for Chemistry Outsourcing: The Challenges of Managing a Lab 8,000 Miles Away.”

  • 27 Mar 2014
  • 5:30 PM
  • Frick Laboratory, Princeton University
“Practical Considerations for Chemistry Outsourcing:  The Challenges of Managing a Lab 8,000 Miles Away.”
Cullen Cavallaro, PhD
Bristol-Myers Squibb


Location: Frick Laboratory, Princeton University
Social mixer: 5:30 pm in CaFe, Taylor Commons
Presentation: 6:30 pm in Taylor Auditorium
Dinner: Immediately following presentation, in
CaFe area

Abstract: Over the last several decades, as the approval of new medicines has become increasingly more expensive and difficult, pharmaceutical companies have expanded the use of outsourcing. In order to lower cost and increase the capacity of drug discovery efforts, many companies have made leveraging overseas partners a key feature of their business strategy. What does this mean for the chemists working directly with distant teams operating outside of their company? Frequently they discover that a number of practical hurdles lie in the way and that differences in communication, culture and infrastructure can make chemistry operations seem very different on the other side of the world. Identifying and addressing the practical issues that impact the staging and execution of chemical reactions can greatly improve chances for success. Examples of typical challenges that are encountered and tactics for overcoming them will be presented.

 Biography: Cullen Cavallaro joined Bristol-Myers Squibb in 2000 and currently leads a high-throughput chemistry group that is part of the Synthesis and Analysis Technology Team. He has spent the past eight years at BMS working in parallel medicinal chemistry following five years of hit-to-leads and combinatorial chemistry. In his current role he oversees an ongoing collaboration with a team located in India and previously served as the coordinator
for a multiyear project that was completed in cooperation with a partner company in China. Prior to working at BMS he held positions at two start-up companies, Coelacanth Corp. and Pharmacopeia Inc., working in the areas of automated chemistry, solid phase synthesis and combinatorial chemistry. Cullen has co-authored 18 publications and 19 patents in a variety of areas including: the discovery of chemokine antagonists, protease inhibitors, and PPAR-gamma agonists; heterocyclic chemistry; combinatorial library design and synthesis; solid phase synthesis; and organometallic chemistry. He received a BA in chemistry from Drew University and a doctorate from Princeton University for work in organometallic chemistry.

Reservations: The meeting will be held in Frick Laboratory, Princeton University. The social mixer will begin at 5:30 pm in the CaFe area of Taylor Commons. The lecture will be held in the Auditorium at 6:30 pm followed by dinner in Taylor Commons (CaFe area). Frick Laboratory is located at the east end of the pedestrian bridge on Washington Rd, adjacent to the Weaver Track and Field Stadium. Parking is available in Lot 21, corner of
Faculty Road and Fitzrandolph Road or other lots along Ivy Lane (see http://m.princeton.edu/map/). The seminar is free and open to the public. Reservations are required for dinner, which is $20 ($10 for students). Please contact Louise Lawter at louise.lawter@gmail.com or 215-428-1475 by March 21 to make reservations.

Reservations must be canceled no later than March 26 to avoid being billed for the dinner.
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